基本信息
导师姓名：李玉芹
导师职称： 教授
电子邮箱： yuqinli2004@126.com
个人简介
李玉芹，博士，教授，博士/硕士生导师，湖南省青年骨干教师，湖南省农林食品教指委委员，湖南省食品科学技术协会常务理事，国家公派华盛顿州立大学访问学者，bevictor伟德官网韶峰学者学术骨干。现为国家基金委化学部通讯评审专家、博士后科学基金通讯评审专家，湖南省自然科学基金评审专家，湖南省科技奖励评审专家，广西科技奖励评审专家，湘潭市科技专家，湘潭市工业新兴优势食品产业链专家。主要研究方向为天然产物功能因子及功能性食品，先后主持国家和省部级项目20余项。指导10余名研究生获得国家奖学金、湖南省优秀硕士论文、bevictor伟德官网研究生校长特等奖等奖项。在Chem. Eng. J、Food Res. J、J. Agric. Food Chem、Bioresource Technol、Int J Biol Macromol、Algal Res、J Food Biochem、Curr Med Chem、Amino Acids、Mol Biotechnol、Pharmazie、Biotechnol Lett、World J Microb Biot等刊物发表论文50余篇，获中国授权发明专利13项，湖南省高等教育省级教学成果奖1项，参编教材1部。
研究方向
1)天然产物功能因子提取纯化及改性工艺
2)天然产物功能因子营养健康功效评价
3)天然产物功能基料与功能性食品研发
4)藻菌基特色功能因子精准合成及其功能食品/动物饲料应用
5)农副产品绿色精深加工与高值化材料创制
科研项目
1.国家自然科学基金面上项目（21676228）
2.国家自然科学基金青年项目（21306161）
3.湖南省教育厅重点项目（18A068）
4.湖南省自然科学基金面上项目（2021JJ30657）
5.湖南省自然科学基金联合基金（2024JJ7548）
6.中国博士后基金面上项目（2012M521531）
7.中国博士后基金特别资助项目（2014T70775）
8.湖南省教育厅优秀青年基金项目（16B254）
9.湖南省自然科学基金青年基金（2017JJ3300）
10.湖南省自然科学基金面上项目（13JJ3062）
11.湖南省工业和信息化技术创新项目（SQ2013ECD200067）
主要代表性成果
1. Luo YY, Zhao SS, Fan ZX,Li YQ*, Peng ZF, Zhang YL, Feng SR, Mou JH, Wang ZY, Carol SKL, Li X. Sucrose non-fermenting 1-related protein kinase 2-14 participating in lipid elevating efficacy and biodiesel upgrade by Coccomyxa subllipsoidea. Chemical Engineering Journal, 2025, 505:159607.
2. ZhouR, ZuoWL, XieYX, WangYT, LiC, TangYF, WangZY,LiYQ*. Sodium bisulfite boosted exopolysaccharide production by Auxenochlorella protothecoides: Potential mechanisms harnessing H2O2signaling and carbon reallocation. Bioresource Technology, 2025, 420: 132121.
3. PengZF, ZhongL,LiYQ*, FengSR, MouJH, MiaoYH,LinCSK, WangZY, LiX. Harnessing oleaginous protist Schizochytrium for docosahexaenoic acid: Current technologies in sustainable production and food applications. Food Research International, 2025, 205:115996.
4. Zhong L, Meng X, Zhang YL, Peng ZF, Zhou R, Tang YF,Li YQ*. Cultivation ofAuxenochlorella protothecoidesusing tofu whey wastewater for aquaculture feed production: Integrating resource recovery and microalgal biomass valorization strategy. Bioresource Technology, 2025, 435: 132913.
5.LiYQ, MengX, WangZY, LinX, XuY, MouJH, ZhouR, TangYF, LinCSK, LiX. Utilization of tofu wastewater andNannochloropsis oceanicafor eutrophication mitigation and eicosapentaenoic acid valorization: Advancing carbon neutrality and resource recycling. Chemical Engineering Journal, 2024, 493: 152706
6.LiYQ*, LuoYY, ZhouR, ZuoXH, ZhangY, WangZY, LiX, ZhangX, QinZH, LinCSK. Coculture ofChlorella protothecoidesandCoccomyxa subellipsoideaenhances cell growth and lipid accumulation: An effective strategy for biodiesel production. Chemical Engineering Journal, 2024, 486: 150302
7. ZhouR, ZhongL, JiaST, LuoYY,LiYQ*, TangYF. Preparation and characterization of aspirin–fucoidan complex and its admirable antitumor activity on human non-small cell lung cancer cells. International Journal of Biological Macromolecules, 2024, 263: 130163.
8. TangYF, LiangF, YanY, ZengYL,LiYQ*, ZhouR. Purification and identification of peptides from Hydrilla verticillata (Linn. f.) Royle with cytoprotective and antioxidative effect against H2O2-treated HepG2 cells. Journal of Agricultural and Food Chemistry, 2024, 72(8): 4170-4183.
9. ZhouR, QianY, LeiZY, TangYF,LiYQ*. Production and characterization of exopolysaccharides from salinity-inducedAuxenochlorella protothecoidesand the analysis of anti-inflammatory activity. International Journal of Biological Macromolecules, 2023, 240: 124217.
10.LiYQ*, LuoYY, WangZY, ZouS, MengX, LiuX. Enhancement of carbon bio-fixation and lipid accumulation inCoccomyxa subellipsoideawith triethanolamine CO2absorbent manipulation. Biochemical Engineering Journal, 2023, 198: 109018.
11. TangYF, YanY, LiYY, YangYX,LiYQ*, ZhouR,PengYZ. Paracetamol biodegradation coupling lipid biosynthesis in acclimated microalgaeCoccomyxa subellipsoidea. Biochemical Engineering Journal, 2023, 200: 109308.
12.Li YQ*, Qi ZH, Fan YW, Tang YF, Zhou R. The concurrent production of lipid and lutein inChlorella vulgaristriggered by light coupling nitrogen tactics. Biochemical Engineering Journal, 2022, 182:108435.
13.Li YQ*, Qi ZH, Fan YW, Zhou R, Tang YF. Boosting concurrent lipid accumulation and secretion byCocccomyxa subellipsoideawith glucose coupling glycerol as accelerator. Algal Research, 2022, 67:102838.
14. Bai YN,Li YQ*, Tang YF, Zhou R, Fan YW. Rhizopus oryzae fermentation wastewater nutrient removal coupling protein fodder production by employingChlorella pyrenoidosa.Bioresource Technology, 2022, 362:127858.
15. Wang ZY, Hao LY, Ren Z, Lin SCK,Li YQ*. Metabolic profiling identified phosphatidylcholin as potential biomarker in boosting lipid accumulation in multiple microalgae. Biochemical Engineering Journal, 2021, 174:108130.
16. Wang ZY, Zhou R, Tang YF, Wang ZT, Feng B,Li YQ*. The growth and lutein accumulation in heterotrophicChlorella protothecoidesprovoked by waste Monascus fermentation broth feeding. Applied Microbiology and Biotechnology, 2019, 103:8863-8874.
17. Wang ZY, Luo F, Wang ZT, Zhou R, Tang YF,Li YQ*. The potential growth and lipid accumulation inCoccomyxa subellipsoideatriggered by glucose combining with sodium acetate. World Journal of Microbiology and Biotechnology, 2019, 35:110.
18. Liu TT, Luo F, Wang ZY,Li YQ*. The enhanced biomass and lipid accumulation inCoccomyxa subellipsoideawith an integrated treatment strategy initiated by brewery effluent and phytohormones. World Journal of Microbiology and Biotechnology, 2018, 34:25.
19. Liu TT, Liu F, Wang C, Wang ZY,Li YQ*. The boosted biomass and lipid accumulation inChlorella vulgarisby supplementation of synthetic phytohormone analogs.Bioresour Technol.2017, 232:44-52.
20. Chao W, Wang ZY, Luo F,Li YQ*. The augmented lipid productivity in an emerging oleaginous model algaCoccomyxa subellipsoideaby nitrogen manipulation strategy. World J Microbiol Biotechnol, 2017, 33:160.
21. Liu TT,Li YQ*, Liu F, Wang C.The enhanced lipid accumulation in oleaginous microalga by the potential continuous nitrogen-limitation (CNL) strategy.Bioresour Technol.2016,203:150-159.
22.Li YQ*, Xu H, Han FX, Mu JX, Chen D, Feng B. Regulation of lipid metabolism in the green microalgaChlorella protothecoidesby heterotrophy-photoinduction cultivation regime.Bioresour Technol. 2015, 192: 781-791.
23. Mu JX, Li ST, Chen D, Xu H, Han FX, Feng B,Li YQ*. Enhanced biomass and oil production from sugarcane bagasse hydrolysate (SBH) by heterotrophic oleaginous microalgaChlorella protothecoides.Bioresour Technol. 2015, 185: 99-105.
24.Li YQ*, Han FX, Xu H, Mu JX, Chen D, Feng B, Zeng HY. Potential lipid accumulation and growth characteristic of the green algaChlorellawith combination cultivation mode of nitrogen (N) and phosphorus (P).Bioresour Technol. 2014, 174:24-32.
25.Li YQ*, Yuan ZQ, Chen D, Feng B. Proteomic analysis of lipid accumulation inChlorella protothecoidescells by heterotrophic N deprivation coupling cultivation.Energy Fuels. 2013, 27: 4031-4040.
26.Li YQ*, Yuan ZQ, Chen D, Zeng HY, Feng B, Fang F. Potato feedstock as an organic carbon source for efficient biomass and lipid production by the heterotrophic microalgaChlorella protothecoides.Energy Fuels. 2013, 27: 3179-3185.
27.Li YQ*, Mu JX, Han FX, Xu H, Kong F, Xie F, Feng B. Production of biomass and lipid by the microalgaeChlorella protothecoideswith heterotrophic-Cu (II) stressed (HCuS) coupling cultivation. Bioresour Technol. 2013, 148:283-292.
发明专利
1.李玉芹，穆锦秀，陈迪等.一种筛选微藻积脂调控酶的方法.专利号: ZL 2014 1 0581886.3.
2.李玉芹，王振瑶，周蓉等.一种挖掘甄选微藻油脂合成代谢标志物的方法.专利号：ZL 201811290739.5.
3.李玉芹，雷铮宇，周蓉等.一种具有抗氧化活性的小球藻胞外多糖.专利号：ZL 201911155787.8.
4.李玉芹，雷铮宇，周蓉等.一种具有免疫调节活性的小球藻胞外多糖复合物及其制备方法和应用.专利号：ZL 201911155767.0.
5.李玉芹，钱娅，贾淑婷等.一种改性岩藻多糖化合物及其制备方法和应用.专利号：ZL 202211525744.6.
6.李玉芹，尹帅，齐振华等.一种共培养微藻提高α-亚麻酸油脂产率的方法.专利号：202211216800.8.
7.李玉芹，任站，贾权威等.一种利用碳酸氢盐强化微藻固碳路径提高积脂效率的方法.专利号：202211277914.3.
8.李玉芹，任站，胡雅婷等.一种胶球藻基因及其在调控生长和脂质合成中的应用.专利号：202211321173.4.
